Ms Carlota Mendez Torrecillas

Senior Instrument Scientist

Continuous Manufacturing And Crystallisation

Contact

Personal statement

I have always had a great interest in Science and Engineering because of the impacts that both of these have on our daily lives. Working in pharmaceutical secondary manufacturing brings together both disciplines.   Secondary manufacturing focuses on the conversion of the active drugs into products suitable for administration.   Combining pilot plant and modelling resarch, we work on the introduction of continuous technology instead to traditional batch equipment.   Transition to continuous is challenging but it will reduce the time of production of the drugs besides to create safer and cheaper drugs .

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Publications

Medicines Manufacturing Innovation Centre : research highlights from an industry-academia-government collaboration
Jolliffe Hikaru Graeme, Prostredny Martin, Mendez Torrecillas Carlota, Bordos Ecaterina, Ahmed Bilal, Velazco Maria, Tierney Colette, Devlin Michael, Cabezudo Garcia Nicolas, Markl Daniel, Robertson John
CMAC Open Day 2025 (2025)
Characterisation of a continuous blender : impact of physical properties on mass holdup behaviour 
Jolliffe Hikaru Graeme, Velazco-Roa Maria A, de Juan Luis Martin, Prostredny Martin, Mendez Torrecillas Carlota, Reynolds Gavin, McElhone Deborah, Robertson John
Powder Technology Vol 449 (2025)
https://doi.org/10.1016/j.powtec.2024.120440
A hybrid system of mixture models for the prediction of particle size and shape, density, and flowability of pharmaceutical powder blends
Salehian Mohammad, Moores Jonathan, Goldie Jonathan, Ibrahim Isra, Mendez Torrecillas Carlota, Wale Ishwari, Abbas Faisal, Maclean Natalie, Robertson John, Florence Alastair, Markl Daniel
International Journal of Pharmaceutics: X Vol 8 (2024)
https://doi.org/10.1016/j.ijpx.2024.100298
Outcomes from an industry-academia-government collaboration : Medicines Manufacturing Innovation Centre research highlights
Jolliffe Hikaru Graeme, Prostredny Martin, Mendez Torrecillas Carlota, Bordos Ecaterina, Ahmed Bilal, Velazco Maria, Tierney Colette, Devlin Michael, Cabezudo Garcia Nicolas, Ojo Ebenezer, Markl Daniel, Robertson John
CMAC Showcase 2024 (2024)
Transferable mini-blender performance impact on continuous direct compaction tablets using a modified Kushner-Moore approach.
Jolliffe Hikaru Graeme, Tierney Colette, Bordos Ecaterina, Mendez Torrecillas Carlota, Prostredny Martin, Elkes Richard, Ojo Ebenezer, Robertson John
Computer Aided Chemical Engineering European Symposium on Computer Aided Process Engineering and International Symposium on Process Systems Engineering, pp. 1081-1086 (2024)
https://doi.org/10.1016/B978-0-443-28824-1.50181-2
Loss-in-Weight feeder performance prediction using Machine Learning
Jolliffe Hikaru Graeme, Mendez Torrecillas Carlota, Reynolds Gavin K, Elkes Richard, Verrier Hugh, Devlin Michael, Dickhoff Bastiaan HJ, Robertson John
Computer Aided Chemical Engineering European Symposium on Computer Aided Process Engineering and International Symposium on Process Systems Engineering, pp. 91-96 (2024)
https://doi.org/10.1016/B978-0-443-28824-1.50016-8

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Research Interests

My new role takes place at the new Medicines Manufacturing Innovation Centre (MMIC) , where I am part of a team focused in the development a continuous direct compression (CDC) platform. CDC is a continuous manufacturing process that allows much greater process control than traditional batch-type pharmaceutical manufacturing methods. Its advantages include rapid production of formulations at a range of scales and also shorter optimisation times compared to batch-type processes.   In my role, I will also help to develop a digitally-twinned CDC platform that allows us to understand and optimise the formulation process in digital space. The hope is that this reduces the amount of starting materials needed for optimisation and reduce the overall cost of the technology for the end-user.

 

Professional Activities

A Novel Metrology for Polymodal Particle Size Distributions and Its Beyond Application in Twin Screw Granulation
Speaker
26/4/2018
A Novel Metrology for Polymodal Particle Size Distributions and Its Beyond Application in Twin Screw Granulation
Speaker
26/4/2018
Sci Formulation Forum
Participant
18/1/2018
7th APS International PharmSci Conference
Invited speaker
5/9/2016
Celebrating Collaboration within TIC
Participant
15/12/2015
CMAC Internal Research Day
Participant
25/9/2015

More professional activities

Projects

EPSRC Doctoral Training Grant - DTA, University of Strathclyde | Mendez Torrecillas, Carlota
Halbert, Gavin (Principal Investigator) Robertson, John (Co-investigator) Mendez Torrecillas, Carlota (Research Co-investigator)
01-Jan-2014 - 04-Jan-2019
Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Mendez Torrecillas, Carlota
Halbert, Gavin (Principal Investigator) Robertson, John (Co-investigator) Mendez Torrecillas, Carlota (Research Co-investigator)
01-Jan-2014 - 04-Jan-2019
David Begg / NSF Studentship | Mendez Torrecillas, Carlota
Halbert, Gavin (Principal Investigator) Robertson, John (Co-investigator) Mendez Torrecillas, Carlota (Research Co-investigator)
01-Jan-2014 - 04-Jan-2019

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Contact

Ms Carlota Mendez Torrecillas
Senior Instrument Scientist
Continuous Manufacturing And Crystallisation

Email: carlota.mendez@strath.ac.uk
Tel: 444 7133